Master's Projects

All listed projects are performed in an interdisciplinary research team at the interface of physics with biology. Students will receive compensation of EUR ~440.-/month. Contact me for further information.

The Lipid Nanodisc-Vesicle Transition

Research Question: Understanding membrane protein function is fundamental to quantitative research in membrane biophysics. Polymer-based nanodiscs offer new attractive ways for isolating membrane proteins from their native environment. For many proteins a transformation of the discs into spherical vesicles is highly desirable. Biophysical details of this pathway remain to be uncovered.

Your role: You will support our current research by performing a comprehensive investigation of the lipid nanodisc to vesicle transition.

Methods: Small-angle X-ray scattering, isothermal titration calorimetry and dynamic light scattering. Data will be analyzed using advanced fitting routines.

Your skills/background/interest:

  • Biophysics / physics / physical chemistry
  • Keen to combine experiments, theory and data modelling (programming)
  • Good communicational skills, highly focused and committed
Assoz. Prof. Dipl.-Ing. Dr.techn.

Georg Pabst

Assoz. Prof. Dipl.-Ing. Dr.techn. Georg Pabst Institut für Molekulare Biowissenschaften

Humboldtstr. 50